The present study makes it possible to identify and analyze the policies and the legal and institutional framework in force in relation to APA, in order to take into account PN/APA. It also highlights the achievements and shortcomings in relation to the implementation of the Nagoya Protocol in Burundi and ultimately makes it possible to establish a legal framework for the implementation of the Nagoya Protocol on Access to Genetic Resources and Benefit Sharing (PN/APA).